Enhanced Serum Neutrophil Chemotactic Activity was Noted in Both Early and Late Asthmatic Responses During Lysine-Aspirin Bronchoprovocation Test in ASA-Sensitive Asthmatic Patients

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Enhanced serum neutrophil chemotactic activity was noted in both early and late asthmatic responses during lysine-aspirin bronchoprovocation test in ASA-sensitive asthmatic patients.

To investigate the pathogenic mechanism of late asthmatic response in comparison to early asthmatic response, changes of serum neutrophil chemotactic activity (NCA) using the Boyden chamber method and histamine level using the automated fluorometric analyzer were observed in 13 aspirin (ASA)-sensitive asthma subjects (group I: 7 early responders and group II: 6 dual responders) during lysine as...

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Thirteen atopic patients with asthma volunteered to take part in the study. All had a history of episodic dyspnoea with wheezing or chest tightness on exposure to allergens (house dust, Candida albicans, and wheat flours). None had received corticosteroids therapeutically. Allergen inhalation tests showed that five of the patients had late asthmatic responses alone, four had immediate asthmatic...

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ژورنال

عنوان ژورنال: Journal of Korean Medical Science

سال: 2003

ISSN: 1011-8934,1598-6357

DOI: 10.3346/jkms.2003.18.1.42